Acute Stroke Treatments
- MR RESCUE (Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy): This study is designed to compare the effectiveness of treatment with mechanical embolectomy (clot retrieval) within 8 hours of symptom onset to standard medical treatment, and to identify patients most likely to benefit from therapy based on their brain imaging pattern.
- MISTIE (Minimally Invasive Surgery plus rt-PA for ICH Evacuation): This study, sponsored by Johns Hopkins University, is designed to evaluate the use of rt-PA in patients with bleeding into the brain to see if the clots can be rapidly removed and to determine if removal of clots has an impact on overall patient survival and disability.
- ACHIEVE (Albumin for intraCerebral Hemorrhage Intervention): this clinical trial is testing whether a serum protein known as albumin can minimize the swelling and brain injury caused by a hemorrhage.
- CLEAR (Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage): This study, sponsored by Johns Hopkins University, is designed to evaluate the use of rt-PA in patients with bleeding into the brain and clots in the ventricles to see if the clots can be rapidly removed and to determine if removal of clots has an impact on overall patient survival and disability.
Stroke Prevention
- PROTECT DC (Preventing Recurrence of Thromboembolic Events through Coordinated Treatment in the District of Columbia): The purpose of this study is to determine if in-hospital education coupled with community-based "stroke navigators" can improve compliance with secondary stroke prevention measures and decrease frequency of recurrent stroke.
Recovery
- ICARE (Interdisciplinary Comprehensive Arm Rehabilitation Evaluation): This stroke recovery study is testing an experimental arm therapy called Accelerated Skill Acquisition Program (ASAP), which combines challenging, intensive and meaningful practice of tasks compared to two standard types of therapy.
Stroke Disparities Program:
The mission of this NIH funded grant is to develop integrated program of collaborative research in DC to overcome current gaps in stroke care in underserved populations. The program includes three projects:
- ASPIRE (Acute Stroke Program of Interventions addressing Racial and Ethnic disparities): This study involves a multilevel intervention to demonstrate tPA utilization can be increased within the District of Columbia, a predominantly underserved population.
- PROTECT DC (Preventing Recurrence of Thromboembolic Events through Coordinated Treatment in the District of Columbia): The purpose of this study is to determine if in-hospital education coupled with community-based “stroke navigators” can improve compliance with secondary stroke prevention measures and decrease frequency of recurrent stroke.
- DECIPHER (Differences in the Imaging of Primary Hemorrhage based on Ethnicity or Race): This project is a longitudinal, imaging-based, observational study designed to understand racial differences in primary intracerebral hemorrhage.
