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Necrosis is death of a portion of tissue or an organ in the body. Tissue death occurs when there is not enough blood supplied to the area, whether from trauma, radiation, or chemicals. Once necrosis is confirmed, it is not reversible.
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.